Medium Arithmetic Puzzles

#216: 1 _ 4 _ 8 _ 8 = 10 medium #217: 1 _ 4 _ 8 _ 8 = -6 medium #224: 1 _ 4 _ 9 _ 6 = -5 medium #225: 1 _ 4 _ 9 _ 3 = 7 medium #229: 1 _ 4 _ 9 _ 3 = 12 medium #235: 1 _ 5 _ 2 _ 6 = 15 medium #239: 1 _ 5 _ 3 _ 6 = -9 medium #242: 1 _ 5 _ 4 _ 8 = 11 medium #247: 1 _ 5 _ 6 _ 2 = 16 medium #249: 1 _ 5 _ 6 _ 3 = -9 medium #252: 1 _ 5 _ 6 _ 2 = 15 medium #255: 1 _ 5 _ 8 _ 4 = 11 medium #257: 1 _ 5 _ 8 _ 2 = 9 medium #271: 1 _ 6 _ 2 _ 5 = 15 medium #274: 1 _ 6 _ 2 _ 7 = 10 medium #275: 1 _ 6 _ 2 _ 8 = -5 medium #277: 1 _ 6 _ 2 _ 9 = -6 medium #283: 1 _ 6 _ 3 _ 2 = -8 medium #296: 1 _ 6 _ 3 _ 7 = 14 medium #297: 1 _ 6 _ 3 _ 8 = -6 medium #308: 1 _ 6 _ 4 _ 6 = -8 medium #310: 1 _ 6 _ 4 _ 8 = 12 medium #313: 1 _ 6 _ 5 _ 2 = 15 medium #316: 1 _ 6 _ 6 _ 4 = -8 medium #317: 1 _ 6 _ 6 _ 9 = -3 medium #324: 1 _ 6 _ 7 _ 3 = 14 medium #327: 1 _ 6 _ 8 _ 2 = 10 medium #328: 1 _ 6 _ 8 _ 4 = 8 medium #332: 1 _ 6 _ 8 _ 4 = 12 medium #336: 1 _ 6 _ 9 _ 6 = -3 medium #337: 1 _ 6 _ 9 _ 3 = 9 medium #344: 1 _ 7 _ 3 _ 6 = 14 medium #347: 1 _ 7 _ 4 _ 8 = 14 medium #350: 1 _ 7 _ 6 _ 2 = 10 medium #352: 1 _ 7 _ 6 _ 3 = 14 medium #355: 1 _ 7 _ 8 _ 2 = 11 medium #356: 1 _ 7 _ 8 _ 4 = 9 medium #360: 1 _ 7 _ 8 _ 4 = 14 medium #361: 1 _ 7 _ 9 _ 3 = 10 medium #363: 1 _ 7 _ 9 _ 9 = 6 medium #370: 1 _ 8 _ 2 _ 3 = 12 medium #371: 1 _ 8 _ 2 _ 4 = 8 medium #372: 1 _ 8 _ 2 _ 5 = 9 medium #375: 1 _ 8 _ 2 _ 7 = 11 medium #377: 1 _ 8 _ 2 _ 8 = 12 medium #378: 1 _ 8 _ 2 _ 8 = -4 medium #380: 1 _ 8 _ 2 _ 9 = -5 medium #381: 1 _ 8 _ 3 _ 4 = -5 medium